Neuropsychopharmacology , 33 (9), 21872199
Physiological Role : Epinephrine is produced primarily by the adrenal gland, and plays an essential role in producing various physiological respones under fight of flight conditions in response to stimulation of the adrenal gland by preganglionic sympathetic nerves
A high-sucrose, high-fat diet causes harmful oxidative modification in metabolically active proteins, resulting in maladaptive tissue remodeling and potentially exacerbating diastolic left ventricular dysfunction
Since GLP-1 antagonists slow digestion, they may worsen certain gastrointestinal conditions
GLP-1 medication examples include Ozempic, Rybelsus, Wegovy, Mounjaro, and Zepbound
A pooled analysis of the STEP 1 through STEP 3 trials, published in Diabetes, Obesity and Metabolism in 2022, examined once-weekly semaglutide 2.4 mg in 2,117 participants against 1,262 on placebo